This sharing is for informational purposes, you should definitely consult your doctor for diagnosis and treatment.

Each treatment may offer different results and different duration of effectiveness for each person.

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CGF (CONCENTRATED GROWTH FACTOR) - CD34

(2nd GENERATION PLATELET CONCENTRATE)

MEDICAL TREATMENT AND AESTHETIC APPLICATIONS

Today, PRP "Growth Factors" treatment, which is widely used in surgery, aesthetic and cosmetic dermatology, is now replaced by CGF-CD34 (Concentrated Growth Factor) containing much more intense "Growth Factors and Stem Cell". and started to receive 2nd Generation Platelet Concentrate treatment.

In the PRP method, the platelet cells, which are the coagulation cells in the blood, were used after they were separated and activated (the growth factors in them were released) with special methods. In the CGF-CD34 treatment method, a much more concentrated (concentrated) growth factor and plasma fluid containing hematopoietic (blood-forming) stem cells (CD-34) is obtained with different activation processes.

Although they are often called "stem cells", these cells are not the same as embryonic stem cells, which are the subject of cloning and other kinds of research, but multipotent (multiple cells) that form all blood cells (white blood cell-red cell) and immune system (immune system) cells cells with the ability to transform into a cell or tissue type.

Studies on CGF-CD34 treatment show that not only growth factors but also stem cells called CD34 are obtained with this treatment method. Therefore, it has been observed that CGF-CD34 treatment is a more effective treatment method than PRP.

Regenerative medicine treatments with growth factors are among the most popular treatments of today, and they have been used more in tissue rejuvenation, wound healing and surgical treatments.

Normally, when there is an injury, the first cells to migrate to the injury site are the coagulation cells, which we call platelets. These clotting cells form clusters when they go to that area, and then they stop bleeding by forming a fibrin plug. Afterwards, they activate the tissue repair mechanisms by releasing the growth factors they contain.

PRP treatments have also been developed inspired by this natural mechanism and applications have been made to mimic scar tissue by multiplying the platelets (thrombocytes) in the blood 3-4 times. The CGF-CD34 technique, which is the 2nd Generation Platelet Concentrate, is a brand new method that includes both growth factors and stem cells that carries this method to the next level.

What is CGF-CD34, how is it obtained and what does it do?

CGF-CD34: After the blood taken from the person is separated into its components by centrifugation at four different cycles and times, it produces platelets (coagulation cells), leukocytes (white blood cells), various growth factors and cytokines (proteins and peptides that enable cells to communicate with each other). is the name of the layer that contains it.

· CD34 stem cells and platelets in the blood;

in blood coagulation,
They are involved in the healing and repair of tissues.
On the other hand; They also secrete growth factors that trigger the growth, proliferation, rejuvenation of cells, repair of damaged tissues and natural healing processes.
Normally, when any damage occurs in our tissues, platelets (thrombocytes) in the blood migrate to this tissue and initiate the repair process. Since the aging process is quite slow, our body does not consider this chronic process as a sudden trauma (injury) and does not direct the restructuring cells to places where they are not needed.

· The purpose of anti-aging application with CGF-CD34; The aim is to deliver a much larger number of platelets to the target tissue than can be carried by the blood circulation in a way that mimics the scar tissue and to trigger restructuring. The density of platelets obtained with CGF-CD34 is 2 to 5 times higher than that in blood. With this method, which is applied with the mesotherapy method, a controlled scar tissue is formed and a much more intense amount of platelets and growth factors than in the blood initiates the restructuring.

Apart from anti-aging purposes, it is also used in musculoskeletal diseases, healing of injured areas, treatment of wounds and burns and hair loss.

There are studies showing that platelet and leukocyte-rich plasma increases cell proliferation, differentiation, blood supply and connective tissue between cells.

It also has FDA approval.

HOW IS CGF-CD34 APPLIED?

First, blood is drawn from the person. Afterwards, concentrated growth factors are obtained by special separation methods. The application area is cleaned with disinfectant and local anesthetic creams are applied.

Obtained plasma;

direct injection,
mesotherapy,
Microneedling ,
in mask,
It can be applied on the wounds.
The application takes a total of 30-45 minutes with the preparation part.

SITUATIONS WHERE CGF-CD34 APPLICATIONS ARE USED FOR TREATMENT PURPOSES:

In the treatment of fibromyalgia, sprains and sprains,

Joint calcifications (knee, hip, shoulder, ankle),

Cartilage - bone wear and calcification (gonarthrosis and patella tendinitis),

· Joint, ligament and muscle injuries,

· Meniscus injuries and tears,

· In the heel spur,

· In waist and neck hernias,

In wound and burn treatments (diabetic foot, in the treatment of non-healing wounds and burns),

In chronic low back and neck pain,

In inflammatory muscle diseases and rheumatic diseases,

· In muscle-connective tissue adhesions,

· In skin adhesions and thickenings,

It can be used in the treatment of hair loss.
 

AESTHETIC CGF-CD34 APPLICATIONS

The aging of our skin occurs with chronological aging. The aging process occurs very slowly and chronically. Many genetic and environmental factors play a role in this process, and tissue repair mechanisms do not know this process very well. For this reason, we try to imitate what our body does when healing a wound in practices aimed at rejuvenating our skin.

In the CGF-CD34 application, what we actually do is to increase the healing capacity of the body. For this reason, in this chronic process, we intensively give these repair cells under the skin, which are not directed to the skin.

In which areas of the skin can CGF-CD34 applications for AESTHETIC PURPOSE be used?

One hundred,
Neck,
decollete,
hands,
hair,
Inner legs-cellulite areas,
To all body parts that are drooping like arms;
 It can be applied for wrinkles, sagging, anti-aging, scar treatment, lifting effect, crack treatment, hair loss.
How many sessions is the CGF-CD34 application for AESTHETIC PURPOSE?

Scientific studies are not sufficient to give definite information on this subject. However, as in PRP treatment, it is recommended to apply 3 sessions with 2-3 week intervals.

In some cases, the number of sessions can be increased to 4-6.

While 3 sessions of cures once a year are sufficient for people under the age of 35 -45, 2 treatments can be applied every 6 months over the age of 45. Age is not the only factor, but general health and lifestyle are also very important. For some people, it is sufficient to repeat the cures once in 2 years.

When does the effect of CGF-CD34 for AESTHETIC PURPOSE start and how long does it last?

Thanks to the stimulus of improvement in CGF-CD34 injection, the results are usually slow, but permanent.
Although the benefits are generally seen after the first injection, the full efficacy becomes noticeable after the 3rd session.
Activity;
During menopause,
Smoking, alcohol use,
In malnutrition,
poor sleep pattern,
It will be shorter if it is not protected from the sun and ultraviolet rays.
As with all treatments, the results are completely personal in this method because everyone's genetic structure and lifestyle are different. Some people have a partial recovery, while others can see a full recovery.

In many scientific studies, it is stated that the success rate is 80-85%.

Some studies have shown that the healing process still continues even after 6 to 9 months of application.

Are there any side effects of CGF-CD34 application for AESTHETIC PURPOSE?

In the CGF-CD34 treatment, which does not have any side effects, there is no risk of allergy, disease transmission and tissue incompatibility since no foreign substance is given from the outside and only the person's own blood is used.

Since it is given by injection (mesotherapy), it has no side effects other than bruising, slight bleeding, redness, edema, infection (if personal hygiene is not taken care of), burning and slight pain.

· Bruising is not seen in everyone. Other side effects disappear quickly within a few hours-days.

After the treatment, the person can continue his daily life, only 4 hours of water and make-up contact is not desired. Very hot bath, shower, Turkish bath, sauna and heavy exercises are not recommended for the first 24-48 hours.

Who should not be applied CGF-CD34 FOR AESTHETIC PURPOSE?

In people with insufficient platelet count in blood count (hemogram) tests,

Those who have an active infection,

Bleeding disease or those who use high amounts of “blood thinners” on the same day,

Those with Chronic Liver Disease (such as cirrhosis, hepatitis),

It is NOT applicable to people who have a history of cancer in the last 5 years.

What should be considered after CGF-CD34 application for AESTHETIC PURPOSE?

It is recommended not to wash, clean and make up the application area for 4-6 hours.

It is necessary not to enter the pool and the sea for 12-24 hours.

· Anti-inflammatory (ie, rheumatic-pain reliever) drugs are not used after injection as they suppress the natural healing process stimulated by CGF-CD34.

However, if pain persists (very, very rarely) due to CGF-CD34 administration, Paracetamol type pain relievers can be used or cold application can be made.

Very hot bath, shower, Turkish bath, sauna and heavy exercises are not recommended for the first 24-48 hours.

What are the advantages of CGF-CD34 FOR AESTHETIC PURPOSE?

No external chemicals or drugs are applied,

It is a natural composition obtained from the person's own blood,

Does not have allergies or other side effects,

There is no risk of infectious disease,

· It is a short-term application,

Its effect starts in a short time,

Its effect is permanent and long-lasting,

· The application is easy and practical.

· Does not require hospital-operating room conditions,

It has similar effects to filling and mesotherapy effects and can be used in combination with these methods.

All procedures performed on the skin and subcutaneous tissues such as Prp, Cgf-Cd34, Fillers, Botox, Mesotherapy, Roller-Micro-Needling Treatments, Laser Treatments, Thread Face Lift Procedures, Spider Web Treatments etc. are medical procedures and should only be applied by doctors.